
Onset : 20 - 90 minutes
Duration : 6 - 10 hours
Normal After Effects : 2 - 6 hours
Light : 5 - 10 mg
Common : 10 - 15 mg
Strong : 15 - 30 mg
Heavy : 30 - 40 mg +
2C-E (2,5-dimethoxy-4-ethylphenethylamine) is a psychedelic and phenethylamine of the 2C family. Its chemical synthesis was first published in 1991 within the book PiHKaL: A Chemical Love Story by Dr. Alexander Shulgin and Ann Shulgin. This was a groundbreaking book that included detailed synthesis instructions for over 200 psychedelic compounds (most of which Shulgin discovered himself) including bioassays, dosages, and other commentary. For those who are interested, 2C-E’s specific entry, synthesis, and qualitative commentary can be found here.
The mechanism that produces the psychedelic effects of 2C-E is a direct result from its action as a 5-HT2A serotonin receptor agonist in the brain. It is a mechanism of action shared by all other hallucinogenic tryptamines and phenethylamines.
Many people have reported that the general effects of 2C-E are similar to those of the other psychedelic phenethylamines, but far more intense in terms of its physical body load and visual effects. The experience is often described as similar in appearance to LSD, and many reports indicate that the effects of this particular chemical may be overly intense for those who are not already experienced with psychedelics.
The 2C-E experience contains a complex and wide array of effects which based on the predefined potential subjective effects index found here, I will now begin to breakdown and describe.
Physical Effects:
The physical effects of 2C-E can be broken down into five components all of which progressively intensify proportional to dosage. These are described below and generally include:
Cognitive Effects:
The head space of 2C-E is described by many as one which is both insightful and relatively normal in its thought processes even at moderate to high dosages.
The total sum of these cognitive components regardless of the setting generally includes:
Visual Effects:
Enhancements
2C-E presents a full and complete array of possible visual enhancements which generally include:
Distortions
As for visual distortions and alterations, the effects experienced are detailed below:
Geometry
The visual geometry that is present throughout this trip can be described as more similar in appearance to that of 4-AcO-DMT or ayahuasca than that of LSD, 2C-B, or 2C-I. They can be comprehensively described as structured in their organization, organic in geometric style, intricate in complexity, large in size, fast and smooth in motion, colourful in scheme, glossy in colour, sharp in their edges, and equally rounded and angular in their corners. They give off a contradictory natural and synthetic feel to them that at higher dosages are significantly more likely to result in states of Level 7B visual geometry over Level 7A.
Hallucinatory States
2C-E produces a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics. This holds particularly true in comparison to other substances within the the phenethylamine family. These effects include:
Auditory Effects:
The auditory effects of 2C-E are common in their occurrence and exhibit a full range of effects which commonly include:
Health Effects, Potential Addiction and Tolerance:
The toxicity and long term health effects of recreational 2C-E use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because 2C-E is a research chemical with very little history of human usage. Anecdotal evidence from people who have tried 2C-E within the psychedelic community suggest that there are no negative health effects attributed to simply trying this drug at low to moderate doses or using it very sparingly (but nothing can be completely guaranteed).
The biggest danger with this substance seems to be confusing it with other more potent psychedelics such as Bromo-DragonFLY as 2C-E which is active in the 200 - 800 microgram range. This means that it is roughly as potent as LSD and extremely dangerous if taken in place of 2C-E, which has resulted in fatal overdoses on multiple separate occasions thanks to the accidental mislabelling of bags from research chemical vendors. There are cases in the media of people ordering 2-CE, among other research chemicals, from online vendors, and receiving Bromo-DragonFLY instead.
2C-E does not seem to physically addictive but could potentially become habit-forming as there is no real tolerance attributed to this drug– meaning that it could potentially be used multiple days in a row if somebody chose to do so. This can be prevented by manually limiting your usage of the drug and is practically unheard of, with most users noting that the desire to use them can actually decrease with use thanks to its powerfully introspective and mentally therapeutic effects.
Legal Issues:
Elsewhere in the world, it is completely legal. If you want to try 2C-E despite full knowledge of the legal risks it can be purchased online through various research chemical vendors of which I cannot legally mention the names of. This means that if you want to do this, you will have to find a source for yourself using the power of Google search.
Conclusion:
In conclusion, I was extremely impressed with 2C-E and it exceeded my expectations many times over. I was originally expecting a poor man’s LSD with psychedelic visuals but no true hallucinatory states. Instead I found myself with a substance that is more comparable to mushrooms and extremely useful for both psychonautical exploration and recreational activities such as raves, festivals, and parties (for those who are already experienced with the substance). It is even useful when taken at very low sub threshold dosages as a motivating background stimulant as I actually wrote this entire article on approximately 0.07mg and it genuinely helped me keep the words flowing and maintain a strong sense of focus.
Alexander Shulgin has been quoted as saying “Someday, the full character of 2C-E will be understood, but for the moment, let it rest as being a difficult and worth-while material. A very much worth-while material.”
This is a statement which I completely agree with and I genuinely hope that this article has contributed to increasing the psychedelic community’s understanding of this fascinating substance.
Over the upcoming months I will definitely be slowly working my way through Shulgin’s magical half-dozen (which can be found here) and documenting each of their subjective effects in as much detail as human English will possibly allow me to.
Click here for a more comprehensive breakdown.
I am writing this article to formally categorize a previously undocumented component of the psychedelic experience and the information which it has revealed. Until recently, my own research had resulted in visuals being broken down into six basic levels, which are described in detail on this page here. Generally speaking, these levels start with fleeting motions, patterns and colours. These eventually lead onto indescribably complex and fast moving colourful geometric patterns, capable of becoming so all encompassing that they begin to block out the entirety of the external environment. The sixth and final level is a state in which every point across your brain feels like it has become interconnected with every other point. You suddenly find your self in an overwhelming state that can only be described as becoming and being able to feel every single thing within the entire universe all at once. This is manifested in the form of an infinite ocean of non-euclidean geometry that can be felt at every single point of detail across itself. Contained within it are innately understood geometric representations of every single concept and neurological structure within the subconscious mind.
Recent experiences with mushrooms and 4-AcO-DMT however have lead me to the conclusion that there is not one singular pinnacle of the psychedelic experience and that a state of equal intensity exists along side it. It seems that depending on subtle environmental factors and the psychedelic consumed, visuals are capable of forking off into two separate versions of their highest level. The deciding factor between the two options appears to be almost random, meaning that from this point forward, level 6 visuals will be separated into two distinct categories.
The first being level 6a - exposure to the entirety of your neurological structure, described above and commonly found on more stimulating psychedelics such as LSD and the 2Cx family.
The second being level 6b - exposure to the inner mechanics of human consciousness. A state which is commonly found on more sedating, hallucinatory psychedelics such as mushrooms or 4-AcO-DMT.
Once psychedelic visuals have reached their final stage, at level 6a or b, they begin to become structured and organized in a way that that presents genuine information to its tripper far beyond the preceding five levels. This is done through the experience of innately understood geometric representations that feel as though they depict specific concepts and neurological components that exist within the brain. This is done in such a way that the concepts can be seen embedded within your closed or open eye visual field whilst simultaneously felt through a physical sensation at every point of detail across itself.
It can be described as the profound feeling of becoming completely detached from the external environment and/or self and falling into a place that is universally interpreted by anybody who undergoes the experience as “the inner workings of the universe”. This is a place that feels as if you have literally entered the very source of existence, with the underlying programming of reality and the true nature of our consciousness presenting itself to you in the most incomprehensible manner. I have been aware of this state for a number of months but it has taken me a total of eight separate extremely high dose trips as well as the participation and input of others to even begin to formulate my words in a way that is logically consistent, comprehensive and understandable to both myself and other people. In order to do this, I will have to break this new component down into its two main sub categories and describe them separately in as much detail as human English will allow.
Becoming the organization and structure of the conscious mind,
At the lower end of level 6b visuals, the experience manifests itself as a new found and consistent ability to feel and see the organization and structure of your current thought stream. This is presented to trippers in the form of a fast moving and infinite web or network of visuals that branch off of each other in a level of organization and intricacy far beyond any possible arrangement that could be experienced within the external physical world.
The ever shifting network follows the pace and rhythm of your internal dialogue perfectly. This creates and manifests new connections in a way that is both physically felt through a powerful sensation and seen embedded within your visual field every time any piece of new insight or knowledge.
This vast network of visuals contains within it, an innately understood, thought stream relevant, geometric representations of specific and abstract concepts embedded into each and every one of the connecting points across itself. The experience of these innately readable geometric representations triggers the mind’s eye to envision the concept perfectly on an internal visual field which exists separately from this one.
Becoming the organization and structure of the subconscious mind,
At the higher end of level 6b visuals, the experience manifests itself as a new found and consistent ability to physically feel, see and become one with the architecture of the subconscious mind. This is presented to trippers in the form of extremely vast and complex, self transforming geometric mechanisms which are immediately interpreted by anybody who undergoes the experience as the inner workings of the universe or reality. This is a state that is capable of bestowing specific pieces of information onto trippers regarding the nature of reality and human consciousness through the simple experience of them. These specific pieces of information are always immediately felt and understood to be a profound unveiling of an undeniable truth at the time, but usually found to be ineffable afterwards; due to the limitations of human English, or nonsensical due to the disorientation of the accompanying ego death, memory loss and hallucinations.
Occasionally however, genuine lessons or coherent messages are innately interpreted through the experience of becoming and descending down into the subconscious faculties of the brain. It’s extremely important to note however that the scientific validity of these lessons is very uncertain and should never be accepted as fact. Every good skeptic knows that anecdotal evidence is next to worthless in terms of the physical data it provides simply, because it is impossible to distinguish between which details are fact and which are hearsay. However, this should never prevent us from acknowledging the importance that these things need to be discussed and explored on a much greater level than we as a society are currently pursuing. This makes these experiences a very good indicator of the direction that future legitimate scientific research and studies should be taking themselves into.
It’s here in this article that I am going to explain some of the specific insights regarding existence and consciousness that have been gained through myself, my girlfriend and a close friend journeying into these states and documenting the experience through means of written interviews and audio recordings in order to make sense of it.
I honestly do not understand any of this myself. They are always felt to be undeniable “truths” at the time but we should not lose sight of the fact that we are deliberately ingesting drugs which trigger imagined hallucinations. I do not claim any position of authority regarding the truth of anything that I am about to tell you. So please keep in mind that I possess no academic credentials whatsoever and have already told you on multiple occasions to disregard everything that I say. I am simply describing and documenting our personal experiences which may well be profound truths or could perhaps simply be the product of hallucinatory delusions undergone by a small group of teenagers on various psychedelic drugs, resulting in unusually elaborate stoner talk.
The first of these so called “truths” and the least important of them, was revealed in the form of being presented with and becoming the mechanisms behind an internal neurological drive which encourages a suspicion of or belief and reverence for a higher system of order than our day to day lives. This is something that was shown to have manifested itself throughout all of human history and culture in a huge variety of religions and superstitious beliefs, existing as an integral part of our psyche, simply because it is an evolutionary advantage in terms of motivation and survival for our lives to be put into this sort of context.
The second of these “truths” was being presented with or shown the true mechanisms behind the brain’s decision making process in any given situation. This clearly showed that the ego, and the internal thought stream which it generates, is an after product of our subconscious’s decision making processes and not in anyway the true director of it. Our current thought stream, emotions, perception of the world, sense of the present situation and what we are doing is being generated instantaneously on a subconscious level as a direct result of our current sensory input. With the ego simply being the experience of the thoughts and decisions after they have already been generated and not something which is capable of controlling itself or any other decision which we make.
The psychedelic and geometric unveiling of this “truth” resulted in the feeling that the human organism is just a complex and immediate chemical reaction to the sensory input fed into us through the external environment. Leading onto the feeling that objects within the external environment which you choose to interact with, pull you towards them as an instant reaction to their presence in a very powerful way, instead of your ego consciously deciding the actions that it is going to perform in advance.
This creates the sensation that we as human beings are comprised of multiple interdependent systems, which all direct themselves and each other as whole. Not a system which is governed by an intrinsically separate and central command centre which our egos have all been raised into thinking that they are.
The third of these apparent “truths” which multiple people throughout my immediate social circle have undergone on several separate occasions has already been documented towards the end of this page here. It has been named as states of unity and interconnectedness, a universally experienced component that is not consistently triggered every time somebody undergoes an appropriately high dose trip. Instead, it occurs spontaneously within people who are currently undergoing states of psychedelic exposure to the inner mechanics of human consciousness and seemingly triggered by very subtle environmental factors of which I do not yet currently understand the relationship between.
In terms of how this state subjectively feels, it begins by stemming from what feels like an awakening or the lifting of a great illusion that is deeply embedded within the human psyche. An illusion that feels as if it is in place to keep human beings feeling as if they are intrinsically separate from and more significant or important than, the external environment. It feels as if it exists due to the strong evolutionary need to keep a person’s perspective on the world as one that prioritizes the needs of the self over the needs of the external, as a means of ensuring the motivation for survival.
The psychedelic disintegration of this apparent illusion is commonly described as a loss of perceived boundaries between the physical body and the external environment, giving the profound sensation that you can no longer understand where your physical body ends and the external environment begins. Our central centre of self with which we identify as “ourselves” is at this point, revealed to be illusory and not any single component of our being, such as the ego, the brain as a whole or even the body in its entirety. Instead, the central centre of self with which we identify with becomes no single component of existence but all of it in its entirety, creating the sudden undeniable perspective that you are literally the entire universe experiencing itself and performing actions onto itself through the very specific point of space and time which your ego happens to reside in. The ego or self as separate from external systems of behaviour is felt to be an elaborate fabrication, that the skin is not what separates us from the universe but what connects us to it. This is a feeling that when experienced is immediately and universally understood to be an undeniable truth by anybody who undergoes it.
I am honestly still trying to wrap my head around this specific mental component and do not feel that I have come close to understanding it or processing its consequences. My current level of experience only allows me to describe the feeling of it and not in anyway the logic behind it.
Similar notions of unity seem to be discussed heavily in Buddhism, Eastern mysticism, Gnosticism, Monism, Non-duality and Alan Watts lectures, as well as basic molecular biology and physics, not to mention various trip reports across the internet that all describe sensations of “becoming one with the universe”.
I somehow feel that this will one day become the default perspective through which humans beings look at the world. In my opinion, this is by far the most profound mental component of the psychedelic experience.
Once a tripper begins to sober up and come down the sensation is usually shown to be non permanent and reduced to something that is understood through logic, but not felt. On rare occasions however, it does seem to become a fully grounded and uncontrollable perspective that can last anywhere from weeks to a lifetime after the trip. This creates obvious and powerful changes in personality that result in a completely selfless perspective which values the well being of the external as on par with the importance of the ego.
Conclusion:
The above descriptions are based on very specific experiences and trips which me and my immediate social circle have undergone. As for the “truths” which were experienced, we have actually been through several but these are the only ones which could be adequately explained so far. I am certain that there are many more to experience and will repeatedly enter the inner mechanics of human consciousness over the upcoming months, increasing my dosage and pushing my brain to its very limits.
It’s important to note that currently, only one of these truths can be known for certain to be a universally experienced component, which is states of unity and interconnectedness. The profoundness and intensity of which is making it genuinely difficult not to get carried with mysticism and irrational beliefs. Even as a skeptical atheist, undergoing the experience of what feels like an internally embedded, chemically induced religion that has existed within human beings all along is extremely fascinating because it does not feel like an irrational perspective in any way. It consistently results in a general reverence and profound sense of awe for higher systems of order which transcends superstitious beliefs and has become so powerfully strong that I literally couldn’t ignore it if I tried. Despite the fact that it is still very difficult for me to pinpoint and explain in any adequate way to those who are not familiar with the experience.
When the importance of psychedelics is finally recognized and psychonautics becomes a legitimate field of science, I am certain that we will learn more about human consciousness and our place in the universe than many people ever suspected possible. This is getting to the point where we can begin to figure out the mechanics of human consciousness from the inside, instead of from above, which is currently the only scientific approach. The same difference between looking at a planet through a telescope and sending a manned mission to explore its surface.
If you have any personal experiences with this state or disagree with anything that I have said, there is now a section below each article which allows you to comment and provide your input, which I strongly encourage as I am extremely interested in hearing what others have to say for purposes of coming to a greater understanding of these ineffable states.

Onset : 30 - 120 minutes
Duration : 4 - 8 hours
Dosage,
Low : 250mg / 250mg
Medium : 300mg / 300mg
Strong : 350mg / 350mg
Heavy : 400mg / 400mg
This article is going to serve as a complete breakdown and categorization for the consistent subjective effects that are induced across all people who undergo the DXM and DPH combination experience. This is something that I am writing because, although there are an infinite amount of possible drug combinations, almost all of them simply induce the effects of the two separate drugs on top of each other in a very predictable manner. However, these two substances do just the opposite of that, producing a very unique synergy when taken together, potentiating the positive aspects of the other substance whilst simultaneously suppressing its negative side effects; all with distinct visual and hallucinatory effects that are found on neither of these substances when taken on their own.
If you are not familiar with the effects or chemistry of either of these substances, you can learn in detail about DXM by clicking here, along with a similar analysis and breakdown of the DPH trip right here. The DXM/DPH experience contains a complex and wide array of effects which based on the predefined potential subjective effects index found here, I will now begin to breakdown and describe…
Physical effects:
When taken in combination, DXM and DPH both lessen the negative side effects of the other substance. For example, DPH’s nausea suppressing abilities the nausea associated with DXM is almost entirely abscent. In return, DXM’s dissociating and anesthetic-like qualities have an extremely positive effect on the unbearably strong physical dysphoria found within DPH. This completely eliminates the muscle cramps, nausea, dizziness, drowsiness, restless leg syndrome, and extreme dehydration experienced when DPH is tried by itself. This allows the unique delirium, hallucinations and visual effects of the DPH experience to become much more accessible to your average person.
The subjective physical effects of DXM and DPH can be broken down into four components all of which progressively intensify proportional to dosage.
These components generally include:
Cognitive effects:
The emotional dysphoria, paranoia, anxiety, depression and feelings of impending doom usually found within DPH do not seem to present when taken in combination with DXM. This could be attributed to DXM’s euphoric and calming effects. In total the subjective cognitive effects of DXM and DPH can be broken down into four components all of which progressively intensify proportional to dosage.
These components generally include:
Visual effects:
Suppression
This combination does not enhance visual stimuli in the way that psychedelics do, instead they tend to degrade and decrease visual aptitude both increasing hallucination and degrading vision.
Distortions
As for visual distortions and alterations, effects experienced are detailed below:
Geometry
In terms of the specific style of geometry present within this combination, they can be described as intricate in complexity, slow in movement, dark in colour scheme and ominous in emotional vibe. They manifest themselves in a traditional psychedelic manner when the eyes are closed but appear as static, unmoving shapes and geometry which the external environment morphs into when the eyes are open and looking at any single point, always resetting once the person double takes. This is an unusual visual effect because both dissociative and psychedelic visuals do not do this, instead preferring to manifest themselves as a fast moving and flat translucent veil across the visual field which cannot be interacted with.
Hallucinatory states
The hallucinatory states found within this combination are identical in style to that of DPH and other deliriants which are more delirious and uncontrollable than that of any other commonly used hallucinogen. These states alternate between waking external hallucination and internal hallucinatory states.
The effects of such hallucinatory states include:
Auditory effects:
The auditory effects of this combination are extremely consistent in occurrence in comparison to that of LSD and psilocybin and exhibit a range of effects which commonly includes,
Conclusion:
Although this is not an experience that I wish to repeat on any sort of regular basis, the DXM and DPH combination is an extremely fascinating one, making delirium accessible to me in a way that DPH on its own never could. This is something that is owed purely to its horribly dysphoric physical and mental effects. This combination should never be taken by beginners and is not for the faint hearted, due to its very sinister undertones in its hallucinations and general vibe of the trip. If you want to try this drug however, both substances are freely available and unscheduled throughout every country in the world and easily accessible through the power of google search. Keep in mind however that neither of these drugs are 100% physically safe, especially when taken repeatedly on a regular basis. You’ll need to do some independent research on both of these substances before you even consider trying an experience such as this.
Click here for a more comprehensive breakdown.