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AL-LAD, broken down and described

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Dosage (oral):

Threshold : < 20 µg
Light : < 80 µg
Common : 80 - 160 µg
Strong : ~ 300 µg
Heavy : > 300 µg

Duration (oral):

Total Duration : 6 - 9 hours
Onset : 30 - 60 minutes
Peak : 3 - 5 hours
Coming down : 3 - 4 hours
After effects : 2 - 5 hours

6-allyl-6-nor-lysergic acid diethylamide (abbreviated AL-LAD, also known as Aladdin) is a semi-synthetic hallucinogenic psychedelic drug of the lysergamide family, as described by Alexander Shulgin in the book TiHKAL (Tryptamines i Have Known And Loved).

This substance has little to no history of human usage. However, it has recently become commonly marketed along side of LSZ as a legal alternative to LSD through online research chemical vendors.

In terms of its chemistry, the molecule differs in structure to LSD by the simple replacement of the methyl group with an allyl group at the 6th nitrogen. Lysergamides are distinct from both tryptamines and phenethylamines, although the chemical structure is more similar to a tryptamine than a phenethylamine.

In terms of its pharmacology, AL-LAD acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from AL-LAD’s efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

AL-LAD shares many common traits with LSD; it appears to be equal in potency as well as similar in mechanism. However, the progression and duration of effects are compressed due to its metabolic differences.

While the subjective effects are almost identical to that of LSD, AL-LAD is significantly shorter in its duration. In comparison to its structural relative LSZ, it is reported to be more introspective and stoning. It therefore comparatively lies on the opposite end of the spectrum of effects which most lysergamides are capable of producing.

The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely if ever occur all at once but heavier dosages will increase the chances and are more likely to induce a full range of effects.

Physical Effects:

  • Spontaneous tactile sensations - The “body high” of AL-LAD can be described as proportionally intense in comparison to its accompanying visual and cognitive effects. It behaves as a euphoric, fast moving, sharp and location specific tingling sensation. For some it is manifested spontaneously at different unpredictable points throughout the trip, but for most it maintains a steady presence that rises with the onset and hits its limit once the peak has been reached. At moderate to high doses of AL-LAD, this sensation will usually hit its highest level and become so overwhelming that people find themselves writhing on the floor in complete pleasure.
  • Stimulation - In terms of its effects on the physical energy levels of the tripper, AL-LAD is usually considered to be very energetic and stimulating without being forced. For example, when taken in any environment it will usually encourage physical activities such as running, walking, climbing or dancing. In comparison, other more commonly used psychedelics such as psilocin are generally sedating and relaxing.
  • Nausea - Mild nausea is occasionally reported when consumed in moderate to high dosages and either passes instantly once the tripper has vomited or gradually fades by itself as the peak sets in.
  • Enhancement of touch - Feelings of enhanced tactile sensation are consistently present at moderate levels throughout most AL-LAD trips. Once level 8A geometry is reached, an intense sensation of suddenly becoming aware of and being able to feel every single nerve ending across a person’s entire body all at once is consistently present.
  • Increased bodily control

Cognitive Effects:

The cognitive effects of AL-LAD can be broken down into 14 components all of which progressively intensify proportional to dosage. In comparison to other psychedelics such as Psilocin, LSA and Ayahuasca, AL-LAD is significantly more stimulating and fast paced in terms of the specific style of thought stream which it produces and contains a large number of potential effects.

The most prominent of these cognitive effects generally include:

Visual effects:

Enhancements

AL-LAD presents a full and complete array of visual enhancements which generally includes:

Distortions

AL-LAD presents a full and complete array of visual distortions which generally include:

Geometry

The visual geometry that is present throughout this trip can be described as more similar in appearance to that of 2C-B or 2C-I than Psilocin, LSA or DMT. It can be comprehensively described through its variations as primarily intricate in complexity, algorithmic in form, unstructured in organization, brightly lit, colourful in scheme, organic in feel, multicoloured in scheme, flat in shading, soft in its edges, large in size, slow in speed, smooth in motion, round in its corners, unimmersive in depth and consistent in intensity. At higher dosages, it consistently results in states of Level 8A visual geometry over Level 8B.

Hallucinatory States

AL-LAD is capable of producing a full range of low and high level hallucinatory states in a fashion that is significantly less consistent and reproducible than that of many other commonly used psychedelics. These effects include:

  • Transformations
  • Internal hallucinations (Autonomous entities, Settings, sceneries, and landscapes,Alterations in perspective and Scenarios and plots) - Although AL-LAD is technically capable of producing hallucinatory states in a fashion that is on par with psilocin or DMT in its vividness and intensity, these effects are extremely rare and inconsistent in comparison. Whilst traditional psychedelics such as LSA, Ayahuasca and Mescaline will induce internal hallucinations near consistently at level 5 geometry and above, AL-LAD will for most simply go straight into Level 8A visual geometry. This lack of consistently induced hallucinatory breakthroughs means that for most, AL-LAD is simply not as deep of an experience as certain other psychedelics. On the rare occasion that they are induced however, they can be comprehensively described in terms of their variations as lucid in believability, interactive in style, new experiences in content, autonomous in controllability and geometry-based in appearance.

Auditory Effects:

The auditory effects of AL-LAD are common in their occurrence and exhibit a full range of effects which commonly includes:

Physical Health Effects, Potential Addiction and Tolerance:

The toxicity and long term health effects of recreational AL-LAD use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because AL-LAD is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychedelic community who have tried AL-LAD suggests that there is no negative health effects attributed to simply trying this drug at low to moderate doses or using it very sparingly (but nothing can be completely guaranteed).

AL-LAD is non-habit forming and the desire to use it can actually decrease with use. It is most often self-regulating.

An almost immediate tolerance is built to AL-LAD after ingestion, preventing one from experiencing its full effects more often than every 4-7 days unless they increase their dose significantly.

Legal issues:

AL-LAD is currently a legal research chemical in the UK, however it is illegal in the US under the analogue act when sold for human consumption. It is unclear in many countries whether it is legal or not and one should take precaution and assume it is illegal to avoid legal issues.

On June 10th, 2014 the UK ACMD recommended that AL-LAD be specifically named in the UK Misuse of Drugs Act as a class A drug despite not identifying any harm associated with its use.[2]

Conclusion:

AL-LAD induces a worthwhile lysergamide experience which can be described as almost indistinguishable from that of LSD although with a much shorter duration. It is a trip which is equally compatible for both recreational and spiritual settings. I would recommend this substance to anybody who is interested in experiencing a somewhat legal alternative to LSD.

This substance breakdown was written through collaboration between PsychonautWiki contributors Pjosepherum, Josifikins and Oscarette. The full article is available here.

4-HO-MiPT, broken down and described

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Dosage (oral):

Threshold : 5 - 10mg
Light : 10 - 20mg
Common : 20 - 30mg
Strong : 30 - 40mg
Heavy : 40mg +

Duration (oral):

Total Duration : 6 - 8 hours
Onset : 20 - 60 minutes
Initial effects : 15 - 30 minutes
Peak : 3 - 6 hours
Coming down : 3 - 5 hours
After effects : 2 - 5 hours

4-HO-MiPT (miprocin, 4-hydroxy-N-methyl-N-isopropyltryptamine, or hats) is an synthetic compound and a lesser-known psychedelic tryptamine. It is thought to be a serotonergic psychedelic, similar to 4-AcO-DMT, LSD and DMT. Its molecular structure and pharmacological effects resemble those of the tryptamine psilocin, which is the primary psychoactive chemical in magic mushrooms.

This substance is relatively uncommon and has only a short history of human use. It was presumably first synthesized by Alexander Shulgin. Its synthesis is described in his book TiHKAL along with reports by people who had ingested the compound. Shulgin’s trials and other anecdotal information suggest that 4-HO-MiPT is similar in activity to psilocin.

In terms of its chemistry, 4-HO-MiPT is the 4-hydroxyl analog of the substituted tryptamine known as MiPT (N-methyl-N-isopropyltryptamine) as well as the isopropyl homolog and structural analog of 4-HO-DMT (Psilocin).

In terms of its pharmacology, 4-HO-MiPT’s psychedelic effects are believed to come from its efficacy at the 5-HT 2A receptor as a partial agonist. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely if ever occur all at once but heavier dosages will increase the chances and are more likely to induce a full range of effects.

Physical Effects:

  • Spontaneous tactile sensations - The “body high” of 4-HO-MiPT can be described as a pleasurable, warm, soft and all-encompassing tingling sensation. This maintains a consistent presence that steadily rises with the onset and hits its limit once the peak has been reached.
  • Sedation - In terms of its effects on the physical energy levels of the tripper, 4-HO-MiPT is considered by most to be relaxing, stoning and mildly sedating. This sense of sedation is often accompanied by compulsive yawning.
  • Runny nose
  • Watery eyes

Cognitive Effects:

The cognitive effects of 4-HO-MiPT are described by many as extremely relaxing, profound and stoning in style when compared to other commonly used psychedelics such as LSD or 2C-B which tend to be energetic and stimulating. It contains a large number of typical and unique psychedelic cognitive effects.

The most prominent of these typical effects generally include:

Visual effects:

Enhancements

4-HO-MiPT presents a full and complete array of possible visual enhancements which generally includes:

Distortions

As for visual distortions and alterations, effects experienced are detailed below:

Geometry

The visual geometry that is present throughout this trip can be described as more similar in appearance to that of Psilocin, Ayahuasca and 2C-E than LSD or 2C-B. It can be comprehensively described through its variations as intricate in complexity, abstract in form, organic in style, structured in organization, brightly lit and multicoloured in scheme, glossy in shading, soft in edges, large in size, slow in speed, smooth in motion, rounded in corners, unimmersive in depth and consistent in intensity. The visuals have a very “natural” feel to them and at higher dosages are significantly more likely to result in states of Level 8B visual geometry over Level 8A.

Hallucinatory States

4-HO-MiPT and its various other forms produce a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics. These effects generally include:

Auditory Effects:

The auditory effects of 4-HO-MiPT are common in their occurrence and exhibit a full range of effects which commonly include:

Physical Health Effects, Potential Addiction and Tolerance:

The toxicity and long term health effects of recreational 4-HO-MiPT use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because 4-HO-MiPT is a research chemical with very little history of human usage. Anecdotal evidence from people who have tried 4-HO-MiPT within the psychonaut community suggests that there are no negative health effects attributed to simply trying this drug at low to moderate doses or using it very sparingly (but nothing can be completely guaranteed).

There is no current data for the LD50 of 4-HO-MiPT, but it is thought to be high.

4-HO-MiPT does not seem to be physically addictive and many users experience a self-regulating quality. There seems to be a tolerance build up when used consecutively multiple days in a row which requires one to double their dosage each time to achieve the same effects.

Legal issues:

  • Sweden: Sveriges riksdags health ministry Statens folkhälsoinstitut classified 4-HO-MiPT as a “health hazard” under the act Lagen om förbud mot vissa hälsofarliga varor (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of November 1, 2005, making it illegal to sell or possess.[1]
  • United Kingdom: The substance could be considered illegal in the UK under the Misuse of Drugs Act of 1971.
  • United States: 4-HO-MiPT is an unscheduled drug in the United States. However, it is an analog of psilocin, which could lead to prosecution under the Federal Analog Act.

Conclusion:

4-HO-MiPT induces a generic yet worthwhile tryptamine experience which can be described as almost indistinguishable from that of psilocybin mushrooms and 4-AcO-DMT. It also has the same dosage range to that of 4-AcO-DMT and I would recommend this substance to anybody who is interested in experiencing psychedelia.

This substance breakdown was written through collaboration between PsychonautWiki contributors Josifikins and Oscarette. The full article is available here.

2C-T-7, broken down and described

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Dosage (oral)
Threshold : 3 - 5 mg
Light : 10 - 20 mg
Common : 15 - 30 mg
Strong : 10 - 50 mg
Heavy : 25 - 60mg

Duration (oral)
Total duration : 5 - 10 hrs
Onset  : 60 - 90 mins
Come up : 15 - 30 minutes
Peak : 3 - 7 hours
Come down : 1 - 2 hours
After effects : 2 - 4 hours

Dosage (insufflated)
Threshold : 1 - 3 mg
Light : 2 - 10 mg
Common : 5 - 15 mg
Strong : 5 - 20 mg
Heavy : 7 - 25 + mg

Duration (insufflated)
Total duration : 3 - 7 hours
Onset : 5 - 15 mins
Come up : 20 - 60 mins
Peak : 2 - 4 hours
Come down : 1 - 2 hours
After effects : 1 - 2 + hours

2C-T-7 (2,5-dimethoxy-4-propylthiophenethylamine) is a psychedelic phenethylamine of the 2C-x family. It was first synthesized by Alexander Shulgin in his book PiHKAL: A Chemical Love Story. This particular substance is part of the so-called “magical half-dozen” list which refers to Shulgin’s self-rated most important phenethylamine compounds, all of which except mescaline he developed and synthesized himself. They are found within the first book of PIHKAL, and are as follows: Mescaline, DOM, 2C-B, 2C-E, 2C-T-2 and 2C-T-7.

In terms of its chemistry, 2C-T-7 is a substituted phenethylamine with methoxy groups attached to carbons R2 and R5as well as a sulfide chain attached to carbon R4.

In terms of its pharmacology, 2C-T-7 has efficacy at the 5-HT2A receptor as a partial agonist. This is a mechanism of action shared by all of the hallucinogenic tryptamines and phenethylamines. Along side of this, as the 2,5-desmethoxy derivative of 2C-T-7 has been shown to be a moderate monoamine oxidase A inhibitor, this substance may likewise have MAOI effects.

2C-T-7 is a highly dose sensitive psychedelic known for its strong visuals and intense body load. Many reports also indicate that the effects of this chemical may be overly intense for those who are not already experienced with psychedelics. The experience contains a complex and wide array of effects which based on the predefined potential subjective effects index found here, I will now begin to breakdown and describe.

Physical effects:

The physical effects of 2C-T-7 can be broken down into six components all of which progressively intensify proportional to dosage. These are described below and generally include:

  • Spontaneous tactile sensations - The body high of 2C-T-7 is intense but, in comparison to 2C-E or 2C-B, it can be considered mild though is still capable of becoming very powerful and highly physically euphoric. It is similar yet distinct from the body high experienced on 2C-E, 2C-B, and LSD. The sensation itself can be described as intense and will manifest itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves.
  • Stimulation - In terms of its effects on the physical energy levels of the tripper 2C-T-7 is usually considered to be very energetic and stimulating in a fashion that is quite comparable to that of other phenethylamines such as 2C-B, 2C-E and 2C-P.
  • Increased bodily control - Although this component is capable of manifesting itself in a distinct and noticeable fashion for most users it does not generally seem to be as apparent or intense as the same component found within LSD and 2C-B.
  • Enhancement of touch
  • Nausea - Mild to extreme nausea is commonly reported when consumed in moderate to high dosages and either passes once the tripper has vomited or gradually fades by itself as the peak sets in.
  • Loss of temperature regulation

Cognitive effects:

The head space of 2C-T-7 is described by many as one which is both insightful and relatively normal in its thought processes even at moderate to high dosages.

The total sum of these cognitive components regardless of the setting generally includes:

  • Enhancement of current mind state
  • Acceleration of thought
  • Feelings of fascination, importance and awe
  • Time distortion
  • Introspection
  • Outrospection
  • Removal of cultural filter
  • Conceptual thinking
  • Ego suppression, loss and death
  • Thought loops
  • Feelings of interdependent opposites
  • Delusions
  • States of unity and interconnectedness

Visual effects:

Enhancements

2C-T-7 presents a full and complete array of possible visual enhancements which generally includes:

  • Increased visual acuity
  • Enhancement of colour
  • Enhanced pattern recognition

Distortions

2C-T-7 presents a full and complete array of possible visual distortions which generally includes:

  • Drifting (Melting, Flowing, Breathing and morphing) - In comparison to other psychedelics, this effect can be described as highly detailed, slow and smooth in motion, static in their appearance and extremely realistic in style but with a subtle digital/cartoonish form.
  • Tracers
  • After images
  • Texture repetition
  • Colour shifting
  • Scenery slicing

Geometry

The visual geometry that is present throughout this trip can be described as more similar in appearance to that of 4-AcO-DMT or Ayahuasca than that of LSD, 2C-B or 2C-I. They can be comprehensively described as structured in their organization, organic in geometric style, intricate in complexity, large in size, fast and smooth in motion, colourful in scheme, glossy in colour, sharp in their edges and equally rounded and angular in their corners. They give off a contradictory natural and synthetic feel with slightly more mystical and shamanic undertones to them in comparison to other phenethylamines. At higher dosages they are equally likely to result in states of Level 7A visual geometry and Level 7B. There seems to be visual geometry that is extremely similar to 2C-E and 2C-P and can be described as equal in intensity or complexity and equal in proportion to the accompanying cognitive and physical effects.

Hallucinatory states

2C-T-7 produces a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics. This holds particularly true in comparison to other substances within the phenethylamine family. These effects include:

  • External hallucinations
  • Internal hallucinations - In comparison to other psychedelics such as LSD, 2C-T-7 is very high in hallucinations embedded within visual geometry. This particular effect commonly contains hallucinations with scenarios, settings, concepts and autonomous entity contact. They are more common within dark environments and can be described as internal in their manifestation, lucid in believability, interactive in style and almost exclusively of religious, spiritual, mystical or a transcendental nature in their overall theme.

Auditory effects

The auditory effects of 2C-T-7 are more common in their occurrence than many more commonly used psychedelics and exhibit a full range of effects which commonly includes:

  • Enhancements
  • Distortions
  • Hallucinations

Health effects, addiction potential and tolerance:

The toxicity and long term health effects of recreational 2C-T-7 use does not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because 2C-T-7 is a research chemical with very little history of human usage. Anecdotal evidence from people who have tried 2C-T-7 within the psychedelic community suggests that there are no negative health effects attributed to simply trying this drug at low to moderate doses or using it very sparingly (but nothing can be completely guaranteed).

2C-T-7 does not seem to be physically addictive and many users experience a self regulating quality. There seems to be a tolerance build up when used consecutively multiple days in a row which requires one to double their dosage each time to achieve the same effects.

There is no current data for the LD50 of 2C-T-7, but it is thought to be high. Erowid does however have some annecdotal information on fatal dosages occurring at 35mg+ of insufflated dosages.

If 2C-T-7 does have MAOI effects, this could indicate that 2C-T-7 is more likely to induce serotonin syndrome, especially at high dosages, than other serotonergic hallucinogens. This may make it dangerous to combine with certain substances such as MDMA, AMT, Ayahuasca or any substance which releases neurotransmitters such as serotonin or those with similar pharmocological effects.

Legal issues:

  • 2C-T-7 is scheduled in Germany.
  • In Australia, 2C-T-2 and 2C-T-7 are covered by the country’s analogue drug laws.
  • 2C-T-7 is unscheduled in Canada.
  • The Netherlands was the first country in the world to ban 2C-T-7, after being sold in smartshops for a short period. After 2C-T-2 was first banned, 2C-T-7 quickly appeared on the market, but was soon banned as well. 2C-T-7 is a list I drug of the Opium Law.
  • Schedule I in Sweden. 2C-T-7 was first classified as “health hazard” under the act Lagen om förbud mot vissa hälsofarliga varor (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of April 1, 1999 under SFS 1999:58 that made it illegal to sell or possess.
  • In 1999, Alexander Shulgin was sent a copy of a letter from the British Home Office to several of its administrative associates that in effect placed all compounds listed in PiHKAL into Class A.
  • On September 20, 2002, 2C-T-7 was classified as a Schedule I substance in the United States by an emergency ruling by the DEA. On March 18, 2004, the DEA published a Final Rule in the Federal Register permanently placing 2C-T-7 in Schedule I.

Conclusion:

2C-T-7 shows incredible depth on both an insightful and a recreational level with a full spectrum of deep psychedelic effects. It is completely worthy of its position within the magical half dozen and an extremely versatile compound. I would recommend this experience to anybody willing to try it in a safe and sensible manner.

This substance breakdown was written in collaboration with PsychonautWiki admin PJosepherum. For a more detailed breakdown please click the here.

DOB, broken down and described

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Dosage:

Threshold : 0.2 mg
Light : 0.2 - 0.75 mg
Common : 0.75 - 1.75 mg
Strong : 1.75 - 2.5 mg
Heavy : 2.5 - 3.5 mg+

Duration:

Total duration : 7 - 17 hours
Onset / Initial effects : 30 - 90 mins
Coming up : 60 - 90 mins
Peak : 3 - 8 hrs
Coming down : 3 - 8 hrs
After effects : 4 - 8 hrs

Dimethoxybromoamphetamine (DOB), also known as Brolamfetamine and Bromo-DMA, is a psychedelic substituted alpha-methylated phenethylamine, a class of compounds commonly known as amphetamines. The phenethylamine equivalent of this substance (lacking the alpha-methyl group) is 2C-B.

This substance has no history of human usage prior to the 1991 publication of its synthesis and pharmacology in the book PiHKAL (Phenethylamines i Have Known And Loved) by Alexander Shulgin. In modern times it is used as a recreational drug and an entheogen, rarely sold on the streets and almost exclusively obtained as a grey area research chemical through the use of online vendors. It was first synthesized by Alexander Shulgin and described in his 1991 book.

In terms of its pharmacology, this substance acts as a selective 5-HT2A, 5-HT2B, and 5-HT2C receptor partial agonist. Its psychedelic effects are thought to be mediated via its actions on the 5-HT2A receptor.

The DOB experience contains a complex and wide array of effects which based on the predefined potential subjective effects index found here, I will now begin to breakdown and describe.

Physical effects:

The physical effects of DOB can be broken down into six components all of which progressively intensify proportional to dosage. These are described below and generally include:

  • Spontaneous tactile sensations - The body high of DOB is manifested as somewhat intense in comparison to most classical psychedelics. The sensation itself can be described as a constantly present yet somewhat mild energetic pins and needles sensation that encompasses a person’s entire body. It is usually static in its position and felt over every square inch of the skin as if it was coming from behind the users body. Occasionally however it manifests itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves.
  • Stimulation - In terms of its effects on the physical energy levels of the tripper, DOB is usually considered to be extremely stimulating at levels which do not become overwhelming and are encouraged instead of forced. This results in a shakiness and unsteadiness of the hands at high dosages but encourages trippers to move around, run, dance, climb and generally engage in physical activities. The level of stimulation varies between users however with some people reporting it to be somewhat similar to amphetamine in its intensity and others reporting that it is extremely subtle even at higher dosages. In comparison, other more commonly used psychedelics such as psilocin are generally sedating and relaxed.
  • Enhancement of touch - Feelings of enhanced tactile sensation are consistently present at moderate levels throughout most DOB trips.
  • Nausea - Mild to extreme nausea is reported when consumed in moderate to high dosages and either passes once the tripper has vomited or gradually fades by itself as the peak sets in.
  • Vasoconstriction - This effect is usually only present at higher dosages but can be particularly uncomfortable.

Cognitive effects:

The head space of DOB is described by many as one of mental stimulation and a powerful enhancement of a person’s current mental state. Many user report that it may not be as deep as other traditional psychedelics such as LSD or Psilocin and that it is comparatively empty in terms of its insightfulness.

The total sum of these cognitive components regardless of the setting generally includes:

  • Introspection - This component is consistently manifested only in the context of a non-social setting in which the user is alone.
  • Increased empathy, love and sociability - This component is inconsistently manifested only in the context of social settings in which one is within the company of others. These feelings of sociability, love and empathy are a little weaker and less sharp than those found on substances such as MDMA and 2C-B but still prove strong enough to provide long lasting therapeutic effects.
  • Acceleration of thought
  • Time distortion
  • Feelings of fascination, importance and awe
  • Conceptual thinking
  • Enhancement of current mind state
  • Ego suppression, loss and death

Visual effects:

Enhancements

DOB presents a full and complete array of possible visual enhancements which generally includes:

  • Increased visual acuity
  • Enhancement of colour
  • Enhanced pattern recognition

Distortions

DOB presents a full and complete array of possible visual distortions which generally includes:

  • Drifting (Melting, Flowing, Breathing and morphing) - In comparison to other psychedelics, this effect can be described as highly detailed, slow and smooth in motion, static in their appearance and unrealistic/cartoon-like in style.
  • Tracers
  • After images
  • Texture repetition
  • Colour shifting
  • Scenery slicing

Geometry

The visual geometry that is present throughout this trip can be described as more similar in appearance to that of LSD, 25I-NBOME or 2C-B than that of Ayahuasca, Psilocin or 2C-E. They can be comprehensively described as unstructured in their organization, algorithmic in geometric style, intricate in complexity, small in size, fast and smooth in motion, colourful in scheme, glossy in colour, sharp in their edges and equally rounded and angular in their corners. They give off a synthetic feel to them that at higher dosages are significantly more likely to result in states of Level 7A visual geometry over Level 7B.

Hallucinatory states

DOB is capable of producing a full range of low and high level hallucinatory states in a fashion that is significantly less consistent and reproducible than that of many other commonly used psychedelics. These effects include:

  • External hallucinations
  • Internal hallucinations - Although DOB is technically capable of producing of hallucinatory states in a fashion that is on par with psilocin or DMT in its vividness and intensity, in comparison, these effects are extremely rare and inconsistent. Whilst traditional psychedelics such as LSA, Ayahuasca and Mescaline will induce internal hallucinations near consistently at level 5 geometry and above, DOB will for most simply go straight into Level 7A visual geometry. This lack of consistently induced hallucinatory breakthroughs means that for most, LSD is simply not as deep of an experience as certain other psychedelics.

Auditory effects:

The auditory effects of DOB are common in their occurrence and exhibit a full range of effects which commonly includes:

  • Enhancements
  • Distortions
  • Hallucinations

Health effects, addiction potential and tolerance:

The toxicity and long term health effects of recreational DOB use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because DOB is a research chemical with very little history of human usage. Anecdotal evidence from people who have tried DOC within the psychedelic community suggests that there are no negative health effects attributed to simply trying this drug at low to moderate doses or using it very sparingly but nothing can be completely guaranteed.

DOB is not physically addictive and many users experience a frequency self-regulating quality to the drug. Tolerance for DOC seems to be very mild and does not build up without repeated use over a short period of time.

Legal Issues:

  • International: DOB is a Schedule I drug under the Convention on Psychotropic Substances.
  • Australia: DOB is schedule II
  • Canada: Listed as a Schedule 1 as it is an analogue of amphetamine.
  • New Zealand: DOB is Schedule I (Class A) in New Zealand. DOB would also qualify as an “Analogue” under New Zealand’s catch-all Analogues section in Schedule 3 / Class C of their drug laws that would make 2C-I, 2C-E, DOI, DOB, ephedrine, and pseudoephedrine Schedule 3 compounds in New Zealand.
  • Poland: DOB is controlled in Poland.
  • UK: DOB is Schedule I/Class A in the U.K., making it illegal to sell, buy, or possess without a license.

Conclusion:

Although DOB could be considered as bland and generic in comparison to DOC and other more traditional psychedelics, it is still a worthwhile experience and perfect for recreational events. This substance can be generally described as a less insightful version of LSD with a longer duration, generic visual and an emptier headspace.

Click here for a more comprehensive breakdown.

25B-NBOMe, broken down and described

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Dosage:

Threshold : 100 µg
Light : 100 - 300 µg
Common : 350 - 700 µg
Strong : 700 - 1500 µg

Duration:

Total duration : 8 - 10 hrs
Onset / Initial effects : 15 - 60 mins
Coming up : 60 - 120 mins
Peak : 3 - 4 hrs
Coming down : 1 - 2 hrs
After effects : 5 - 24 hrs

25B-NBOMe or 2C-B-NBOMe is a serotonergic N-benzyl derivative of the substituted phenethylamine psychedelic known as 2C-B.

It has nearly no history of human use prior to 2010 when it first became popular due its ease of purchase from online research chemical vendors.

25B-NBOMe has efficacy at the 5-HT2A receptor where it acts as a potent partial agonist. It was discovered in 2003 by Ralf Heim at the Free University of Berlin, it differs from 2C-B structurally through a substitution on the amine (NH2) with a 2-methoxybenzyl (BOMe) group as shown in the image above. This change in structure results in roughly a sixteen fold increase in potency when compared to 2C-B, allowing even the most extreme of dosages to fit in liquid form onto tabs and blotter paper (which people often mistake for LSD).

There are, however, methods of differentiating between LSD and adulterants like 25B-NBOMe with and without test kits.

For example, one of the key differences between 25B-NBOMe and LSD is that this substance is only active when taken through a sublingual or insufflated route. This means that in order to get the full effects, 25B-NBOMe blotter paper must be lightly chewed on within the mouth for 10 - 20 minutes and never immediately swallowed.

Insufflation, however, is not recommended due to the amount of people who have suffered through dangerous and often fatal overdoses due to this route of administration.

The 25B-NBOMe experience contains a complex and wide array of effects which based on the predefined potential subjective effects index found here, I will now begin to breakdown and describe.

Physical effects:

The physical effects of 25B-NBOMe can be broken down into six components all of which progressively intensify proportional to dosage. These are described below and generally include:

  • Sublingual numbing - assuming the substance has been taken sublingually, the very first physical effect which a person will notice immediately after sublingual absorption is a strong, unpleasant metallic chemical taste. This is accompanied by a very obvious feeling of general numbness of the tongue and mouth which can stay for up to an hour after the blotter paper has been consumed. This is the key difference when it comes to determining whether your blotter paper contains LSD or one of the NBOMe series.
  • Spontaneous tactile sensations - the body high itself can be described as a generally mild, all-encompassing, soft but euphoric tingling sensation. This tingling sensation is also accompanied by spontaneous rushes of euphoria that become longer and more drawn out proportional to the dosage consumed.
  • Decreased bodily weight - in terms of the body’s perceived weight, this substance consistently leaves people feeling extremely light, often to the point of total weightlessness.
  • Stimulation - in terms of its effects on the physical energy levels of the tripper, 25B-NBOMe is usually considered to be energetic and stimulating, but it can be considered less stimulating when compared to 25I-NBOMe. For most people, this substance induces a unique type of physical stimulation which can be described as feeling extremely energetic but in a way which does not force the tripper to move unless they genuinely choose to do so. For others however, the stimulation can be quite uncontrollable, occasionally resulting in bodily shakes and a grinding of the teeth comparable to that of MDMA and traditional stimulants such as amphetamine, but this is manifested much less consistently when compared to 25I-NBOMe
  • Vasoconstriction - it is worth noting that an undetermined percentage of people who experiment with this drug will experience negative physical side effects, such as a temporary difficulty in urinating and vasoconstriction. This is defined as the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels and is triggered through the way in which 25B-NBOMe’s target receptor (5-HT2A) modulates both vasoconstriction and vasodilation among its many other functions.
  • Nausea - as the tripper begins to come up, nausea is not uncommon and can sometimes result in initial vomiting, but passes once this has either happened or the trip begins to fully set in. In comparison to other psychedelics such as psilocin, LSD, 2C-E and 2C-I, this could actually be very considered very mild in its intensity.

Cognitive effects:

The head space of 25B-NBOMe is described by many as remarkably light and underwhelming in comparison to the classical psychedelics. It is not uncommon for people to report feeling that their thought stream has maintained general normality in its specific style throughout low to moderate dosages. At high dosages however, mild to overwhelming cognitive alterations become present.

The most prominent of these cognitive effects generally include:

  • Introspection - this component is consistently manifested only in the context of a non-social setting in which the user is alone.
  • Increased empathy, love and sociability - the entactogenic effects range from mild to powerful, but are inconsistently manifested. entactogenic effects for people who try this substance usually become prominent in the presence of others. These feelings of increased sociability, love and empathy do not seem to be quite as strong or profound as those found within other entactogens (such as MDMA, 2C-B and AMT)
  • Acceleration of thought
  • Time distortion
  • Feelings of fascination, importance and awe
  • Conceptual thinking
  • Connectivity of thought
  • Enhancement of current mind state
  • Removal of cultural filter
  • Ego suppression, loss and death

Visual effects:

Enhancements

25B-NBOMe presents a full and complete array of possible visual enhancements which generally includes:

  • Increased visual acuity
  • Enhancement of colour
  • Enhanced pattern recognition

Distortions

The visual distortions and alterations which are experienced are detailed below:

  • Drifting (Melting, Flowing, Breathing and morphing) - In comparison to other psychedelics, this effect can be described as highly detailed, slow and smooth in motion, static in their appearance and unrealistic/cartoon-like in style.
  • Tracers
  • After images
  • Texture repetition
  • Colour shifting
  • Scenery slicing

Geometry

The visual geometry that is present throughout this trip is often described as similar in appearance to that of LSD. They can be comprehensively described as algorithmic in geometric style, intricate in complexity, fine and zoomed out in detail, fast and smooth in motion, structured in shape, colourful in scheme, glossy in colour, sharp around the edges and mostly rounded across their corners. In comparison to other more commonly used psychedelics they can be described as significantly more intricate than the visual geometry found within 2C-I and most of the 2C-x family in general as well as completely on par with LSD, Psilocin and DMT at appropriately high dosages.

In terms of their behaviour, 25B-NBOMe’s geometry leads onto Level 7A visual geometry with Level 7B remaining so far unconfirmed within this substance. They also seem to consistently build up in visual intensity when the tripper stares at a central point. This eventually envelops the visual field and creates the sensation that the tripper has broken through into a continuously shifting geometric landscape or structure with a vast sense of immersive physical size attributed to it.

Hallucinatory states

25B-NBOMe is capable of producing a full range of hallucinatory states within the level 1 - 3 range extremely consistently. However, level 4 hallucinatory breakthroughs are reported but very uncommon and inconsistent in comparison to other more commonly used psychedelics such as psilocin, 2C-E and DMT.

These effects include:

  • External hallucinations
  • Internal hallucinations - this particular effect commonly contains hallucinations with scenarios, settings, concepts and autonomous entity contact. They are more common within dark environments and can be described as internal in their manifestation, lucid in believability, interactive in style and almost exclusively of religious, spiritual, mystical or a transcendental nature in their overall theme.

Auditory effects:

The auditory effects of 25B-NBOMe are common in their occurrence and exhibit a full range of effects which commonly includes:

  • Enhancements
  • Distortions
  • Hallucinations

Health effects, addiction potential and tolerance:

25B-NBOMe is a very new substance and little is known about its pharmacological or behavioural risks. The LD50 is not known. Some deaths have been attributed to 25B-NBOMe overdose caused by improper handling and uneducated use of this substance. Its recent widespread use suggests that death is primarily caused from overdoses and not from ordinary doses, particularly from insufflation.

The fact that 25B-NBOMe is active in the microgram range is likely a contributing factor since this makes measuring doses significantly more difficult. 

In terms of its addictive potential, 25B-NBOMe has not been studied formally but due to its immediate tolerance build up which lasts up to 2 - 3 weeks after the experience, it is essentially impossible to use this substance compulsively.

Legal issues:

  • UK: 25B-NBOMe is under a temporary class drug order, lasting one year from 10th June 2013.
  • Sweden: 25b-NBOMe is classed as schedule I.
  • USA: On Nov 15, 2013, the DEA added 25B-NBOMe to Schedule I using their emergency scheduling powers, making it “temporarily” in Schedule I for 2 years.

Conclusion:

As for the substance itself, 25B-NBOMe  and the NBOMe series as a whole are an extremely interesting set of psychedelics but do not quite compare in terms of hallucinatory and cognitive depth if you have access to classical psychedelics such as genuine LSD, DMT and psilocin.

Please let me know if you agree or disagree with any particular points contained within this article by using the comment system below.

Click here for a more comprehensive article.

updates updates updates

It may seem that I have been inactive recently due to a general lack of new original posts but I and others have been working extremely hard on overhauling and expanding upon the content within both DEIS and PsychonautWiki. This post is essentially a list of specific updates to inform my readers on the progress, changes and future of this website which can be found below:

  • Psychedelics (Visual/Cognitive/Miscellaneous), Deliriants and Dissociative breakdowns have each received grammatical and descriptive overhauls.
  • New previously undocumented psychedelic cognitive components added: Outrospection, Mindfulness, Multiple thought streams, Personality regression, Thought loops, Feelings of interdependent opposites and Delusions.
  • New previously undocumented dissociative components: Environmental Cubism, Environmental Orbism.
  • Hallucinatory states split into External and Internal hallucination categories for all hallucinogen breakdowns.
  • Documentation article removed and stylistic variations of individual components (Geometry, Drifting, Spontaneous tactile sensations, etc) have simply been integrated into pre-existing articles for hallucinogen category breakdowns.
  • All specific substance breakdowns have been updated to follow a consistent and standardized layout. This no longer describes each effect unless it contains a specific style or variation and instead asks one to refer back to our centralized potential subjective effects index for a detailed explanation.
  • Responsible use page overhauled to be more comprehensive and legitimate.
  • Non hallucinogenic substance categories added to PsychonautWiki with many more to come: Entactogens, Stimulants, Depressants, Nootropics, Opioids, Benzodiazapines.
  • Non hallucinogenic breakdowns added to PsychonautWiki with many more to come: Amphetamine, Methylphenidate, Heroin, Codeine, TramadolModafanilAlprazolam and Cannabis.
  • We now have an extremely active and dedicated community which is constantly progressing www.PsychonautWiki.org as we approach the release of V1.0. We are always looking for contributors and encourage you to visit our active IRC chatroom to talk with myself and other admins.
  • Adverts have been implemented on DEIS. Sorry about this. You are welcome to hide them with AdBlock and an explanation of why this has been done can be found here.

As for the future, we are currently in the process of working on a full release for PsychonautWiki and have ten or so individual psychedelic substance breakdowns to post over up the upcoming weeks.

Thanks for reading and have a nice day <3

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MXP, broken down and described

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Dosage
Threshold : 0 - 50 mg
Light : 50 - 100 mg
Common : 100 - 150 mg
Strong : 150 - 200 mg
Heavy : 200 mg+

Duration
Total duration : 6 - 8 hrs

Methoxphenidine (MXP) or 1-[1-(2-methoxyphenyl)-2-phenylethyl]piperidine is a hallucinogenic dissociative compound of the piperdine chemical class. It has similar effects to that of the arylcyclohexylamine and morphinan classes of dissociatives.

It induces a state referred to as “dissociative anesthesia” and is used as a recreational drug. Very little is known about this substance but it has recently become freely available through online research chemical vendors where it is being sold as a designer drug and marketed as a replacement for MXE despite many users reporting it as qualitatively different in its effects and closer to that of DXM. It has yet to be studied within humans in any formal context.

In terms of its chemistry, MXP is classed as a piperdine drug. The piperdine molecule in MXP is attached to a benzene group via two carbon atoms on one side and a methoxybenzene molecule attached to one carbon on the other side. It is usually produced in its freebase form, which is insoluble in water. When consumed orally, the molecule is converted to the hydrochloride salt in the stomach. The HCl salt is reported to raise blood pressure, and peak effects are felt around 2 hours in, whereas the citrate salt has been observed to peak at around 30 minutes with less blood pressure concern. This is the same principal as DXM which is more potent in its citrate salt.

As for its pharmacology, MXP has antagonistic action on NMDA receptors, which leads to anaesthetic and dissociative effects. Although it has not been formally studied, the feelings of physical and emotional euphoria which many users report suggests that it may also have action as a dopamine reuptake inhibitor.

The MXP experience contains a complex and wide array of effects which based on the predefined potential subjective effects index found here, I will now begin to breakdown and describe.

Physical effects:

The subjective physical effects of MXP are most similar to that of DXM than any other commonly used dissociative. They can be broken down into seven components all of which progressively intensify proportional to dosage. These are described below and generally include:

  • Disconnection from tactile input - this results in typical states of progressive physical disconnection but is far more consciously controllable than that of other dissociatives. This allows one to choose how much of their body they are currently aware of and connected to simply by directing their focus towards it even throughout higher states of disconnection and out of body experiences.
  • Spontaneous tactile sensations - the MXP body high is a soft, pleasurable vibrating sensation. It can be felt all over the body and progressively intensifies throughout the onset before dissipating once the peak has been reached.
  • Suppression of touch - this partially to entirely suppresses one’s own sense of touch, creating feelings of numbness within the extremities. It is responsible for the anaesthetic properties of this substance.
  • Physical autonomy
  • Loss of motor control - a loss of gross and fine motor control alongside of balance and coordination is prevalent within MXP and becomes especially strong at higher dosages. This means that one should be sitting down before the onset unless they are experienced in case of falling over and injuring oneself.
  • Euphoria - this results in feelings of physical euphoria which range between mild pleasure to powerful all encompassing bliss.
  • Decreased bodily weight - this creates the sensation that the body is floating and has become entirely weightless. This effect is strangely stimulating and encourages physical activities at low - moderate dosages by making the body feel light and effortless to move.
  • Dizziness

Cognitive effects:

The head space of MXP is often described as particularly clear headed even at heavy dosages. It is far more controllable, less disorientating and confusing at dosages of equal subjective intensity to that of MXE, DXM and Ketamine. The cognitive effects of MXP can be broken down into 6 separate subcomponents which are listed and described below:

  • Disconnection from consciousness
  • Acceleration of thought
  • Ego suppression, loss and death
  • Time distortion - feelings of time dilation and more time having passed than it actually has are common at moderate to strong dosages.
  • Euphoria
  • Conceptual thinking

Visual effects:

The visual effects of MXP are unique in comparison to other dissociatives as they do not include open eye visual suppression, geometry or distortions but still remain very powerful at appropriate dosages. The present effects progressively intensify according to dosage and commonly include:

  • Disconnection from visual input - this eventually results in the MXP’s equivalent of the famous “K-hole” or more specifically, holes, spaces and voids alongside of level 1 - 4 structures. In comparison to other substances, this effect is unique however as it is far more consciously controllable than that of other dissociatives. It allows one to choose how disconnected they currently are by simply directing their focus towards the external environment even throughout higher states of disconnection and out of body experiences.
  • Internal hallucinations - these hallucinatory states can be described as dream like in nature while often containing imagery, landscapes, plots, settings, autonomous entity contact and scenarios. They are more common within dark environments and can be described as internal in their manifestation, lucid in believability, mostly unimmersive in style and extremely controllable in their content in a way which allows one to choose what they wish to see.

Auditory effects:

The auditory effects of MXP are common in their occurrence but unlike other more commonly used dissociatives, they are unlikely to suppress or distort auditory input and exhibit a small range of effects which exclusively includes:

  • Enhancements

Afterglow:

The afterglow is a feeling that occurs within the 24 hours after the trip itself. It is long lasting and as equally enjoyable as the trip itself to many people. It can be be described in terms of its physical sensation as one of euphoria, rejuvenation, relaxation and a light bounciness. In terms of its mental thought processes however, it can be described as a complete loss of anxiety, feelings of contentedness and an extremely high appreciation for music which dissipates within a day or so after the experience.

Health effects, addiction potential and tolerance:

The toxicity and long term health effects of recreational MXP use does not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because MXP is a research chemical with very little history of human usage. Anecdotal evidence from people who have tried MXP within the community suggests that there are no negative health effects attributed to simply trying this drug at low to moderate doses or using it very sparingly (but nothing can be completely guaranteed).

There is a very strong tolerance build up with MXP which results in the need to consume increasingly large doses in order to achieve the same level of effects. This should reset to baseline after 1 - 2 weeks. There may well be some addictive potential but this is still unknown.

Tolerance may be mitigated via preparing the citrate salt by mixing the chemical with citric acid or lemon juice, which will aid in absorption and increase effects.

Legal Issues:

MXP is currently a legal grey area world wide and freely available through the use of online research chemical vendors. This does not mean that you are guaranteed to be immune from legal prosecution should you be found in possession of this substance as it is likely to vary from country to country.

Conclusion:

This new dissociative is an extremely novel, capable and interesting compound. The potential negative effects are currently unknown so tread carefully and start with light dosages if you are so inclined.

This subjective effect breakdown was made in collaboration with PsychonautWiki user, PJosepherum.

Click here for a more comprehensive breakdown.

2C-I, broken down and described

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Dosage (oral)
Threshold : 2-5mg
Light : 5-15mg
Common : 10-25mg
Strong : 20-30mg
Heavy : 30+mg

Duration (oral)
Total duration : 5 - 8 hours
Onset : 20 - 90 minutes
Come up : 20 - 30 minutes
Peak : 3 - 7 hours
Come down : 1 - 2 hours
After effects : 2 - 4 hours

2C-I or 2,5-dimethoxy-4-iodophenethylamine is a psychedelic phenethylamine of the 2C-x family. It was first synthesized by Alexander Shulgin. It was described in Shulgin’s 1991 book PiHKAL: A Chemical Love Story. The drug is used recreationally for its psychedelic and entactogenic effects and is sometimes confused for the analog 25I-NBOMe. 2C-I is commonly sold in its hydrochloride salt form, which is a fluffy, sparkling, white powder, which can sometimes be pressed into tablet form. 2C-I has been explored as a potential stimulant nootropic in doses between 1-8mg.

In terms of its chemistry, 2C-I is a substituted phenethylamine with methoxy groups attached carbons R2 and R5 as well as an iodine molecule attached to carbon R4. It is thought to have efficacy at the 5-HT2A receptor as a partial agonist.

The 2C-I experience contains a complex and wide array of effects which based on the predefined potential subjective effects index found here, I will now begin to breakdown and describe.

Physical effects:

The physical effects of 2C-I can be broken down into five components all of which progressively intensify proportional to dosage. These are described below and generally include:

  • Spontaneous tactile sensations - The body high of 2C-I is manifested as one of the most proportionally intense in comparison to almost all of the classical psychedelics. The sensation itself can be described as an intense and slightly uncomfortable energetic pins and needles sensation that constantly encompasses a person’s entire body. It is usually felt over every square inch of the skin but occasionally manifests itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves. Alongside of this, many users commonly report that the body high can be particularly uncomfortable and sometimes accompanied by dysphoric aches and urges to shift the position of one’s body and prolonged tensing of unusual combinations of muscle groups.
  • Euphoria - Feelings of frequent but unpredictable rushes of warm physical euphoria are extremely common and very pleasurable. These move from the top of the head downwards before envoloping ones whole body.
  • Stimulation - In terms of its effects on the physical energy levels of the tripper, 2C-I is usually considered to be very energetic and stimulating in a fashion that is quite comparable to that of MDMA although encouraged instead of forced.
  • Increased bodily control
  • Enhancement of touch
  • Nausea - Mild to extreme nausea is consistently reported when consumed in moderate to high dosages and either passes once the tripper has vomited or gradually fades by itself as the peak sets in.
  • Loss of temperature regulation
  • Head aches - Some users report mild but uncomfortable head pressures which can occasionally intensify during the offset of the experience.

Cognitive effects:

The head space of 2C-I is described by many as one which is relatively normal in its thought processes even at moderate to high dosages. It is often said to lack insight when compared to that of 2C-E, 2C-B and LSD.
The total sum of these cognitive components regardless of the setting generally includes:

  • Increased empathy, love and sociability - This component is consistently manifested only in the context of social settings in which one is within the company of others. These feelings of sociability, love and empathy are a little weaker and less sharp than those found on substances such as MDMA and 2C-B but still prove strong enough to provide long lasting therapeutic effects.
  • Time distortion
  • Feelings of fascination, importance and awe
  • Sexual arousal
  • Enhancement of current mind state
  • Ego suppression, loss and death
  • States of unity and interconnectedness

Visual effects:

Enhancements

2C-I presents a full and complete array of possible visual enhancements which generally includes:

  • Increased visual acuity
  • Enhancement of colour
  • Enhanced pattern recognition

Distortions

2C-I presents a full and complete array of possible visual distortions which generally includes:

  • Drifting (melting, flowing, breathing and morphing) - In comparison to other psychedelics, this effect can be described as simplistic and bland in detail, slow and smooth but sometimes jittery in motion, static in appearance and unrealistic/cartoon-like in style.
  • Tracers
  • Symmetrical texture repetition - In comparison to other psychedelics such as LSD and 2C-E this particular effect is bland and simplistic.
  • Colour shifting
  • Scenery slicing

Geometry

The visual geometry that is present throughout this trip can be described as more similar in appearance to that of LSD or 2C-B than that of 2C-E, psilocin, or ayahuasca although it is much more bland and less detailed. They can be comprehensively described as unstructured in their organization, algorithmic in geometric style, intricate in complexity, large in size, fast and smooth in motion, colourful in scheme, glossy in colour, both soft and sharp in their edges as well as equally rounded and angular in their corners. They seem high in algorithmic visuals such as fractals and at higher dosages are significantly more likely to result in states of Level 7A visual geometry over Level 7B.

Hallucinatory states

Like LSD, while 2C-I is capable of producing a full range of low and high level hallucinatory states, this is extremely rare and inconsistent at higher levels but common at lower and generally includes the following effects:

  • External hallucinations - The experience of effects such as open eye transformations are common within 2C-I but not consistent.
  • Internal hallucinations - Although 2C-I is technically capable producing of hallucinatory states in a fashion that is on par with psilocin or DMT in its vividness and intensity, in comparison, these effects are extremely rare and inconsistent. Whilst traditional psychedelics such as LSA, Ayahuasca and Mescaline will induce internal hallucinations near consistently at level 5 geometry and above, 2C-I hallucinations will not extend beyond imagery and higher dosages will for most will simply go straight into Level 7A visual geometry. This lack of consistently induced hallucinatory breakthroughs means that for most, 2C-I is simply not as deep of an experience as certain other psychedelics.

Auditory effects:

The auditory effects of 2C-I are common in their occurrence and exhibit a full range of effects which commonly include:

  • Enhancements
  • Distortions
  • Hallucinations

Health effects, addiction potential and tolerance:

The toxicity and long term health effects of recreational 2C-I use does not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because 2C-I is a research chemical with very little history of human usage. Anecdotal evidence from people who have tried 2C-I within the psychedelic community suggests that there are no negative health effects attributed to simply trying this drug at low to moderate doses or using it very sparingly (but nothing can be completely guaranteed).

There is a short period of tolerance after 2C-I use. Using 2C-I two days in a row is likely to lead to a diminished experience the second day. However, this effect is nearly non-existent when spaced 5-7 days apart.

Legal issues:

  • European Union: In December 2003, the European Council issued a binding order compelling all EU member states to ban 2C-I within three months.
  • Denmark: It is a controlled substance.
  • Germany: It is a controlled substance.
  • Greece: It is a controlled substance.
  • Ireland: The drug is a controlled substance.
  • Italy: It is a controlled substance.
  • Netherlands: It is a controlled substance.
  • Poland: It is a controlled substance.
  • Sweden: Sveriges riksdag added 2C-I to schedule I (“substances, plant materials and fungi which normally do not have medical use”) as narcotics in Sweden as of March 16, 2004. 
  • United Kingdom: It is controlled as a Class A substance.
  • USA: As of July 9, 2012, in the United States, 2C-I is a Schedule I substance under the Synthetic Drug Abuse Prevention Act of 2012, making possession, distribution and manufacture illegal.

Conclusion:

2C-I is a worthwhile experience but is not as deep as other drugs of the same family. It is a substance which works better for some than others. For example, while many find it to be extremely uncomfortable others find it perfect for recreational use in public and social environments. 

This subjective effect breakdown was made in collaboration with PsychonautWiki admin, Oscarette

Click here for a more comprehensive breakdown.

Nitrous Oxide, broken down and described

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Dosage
"N/A - depends on method of consumption"

Duration
Total duration : 1 - 5 minutes
Onset : 0 - 1 minutes
Coming : Up 15 - 30 seconds
Peak : 1 - 5 minutes
Coming down : 10 minutes
After effects : 15 - 30 minutes

Nitrous oxide, commonly known as laughing gasnitrousnitroNOS or hippy crack is an inorganic molecule and chemical compound with the formula N 2O. It is an oxide of nitrogen. At room temperature, it is a colourless, non-flammable gas, with a slightly sweet odour and taste. It is used in surgery and dentistry for its anaesthetic and analgesic effects. It is known as “laughing gas” due to the euphoric effects of inhaling it, a property that has led to its recreational use as an A-typical dissociative anaesthetic. It is also used as an oxidizer in rocketry and in motor racing to increase the power output of engines. At elevated temperatures, nitrous oxide is a powerful oxidizer similar to molecular oxygen.

The gas was first synthesised by English natural philosopher and chemist Joseph Priestley in 1772, who called it phlogisticated nitrous air (see phlogiston). It was first used as an anaesthetic drug in the treatment of a patient when dentist Horace Wells demonstrated insensitivity to pain from a dental extraction on 11 December 1844. Today it is used world wide by hospitals and dentists alike as a general anaesthetic. The recreational use of nitrous oxide began at “laughing gas parties”, primarily arranged for the British upper class in 1799 and has continued into modern times as the gas has become cheaper and more accessible to the masses.

The pharmacological mechanism of action of N2O in medicine is not fully known. However, it has been shown to directly modulate a broad range of receptors, and this likely plays a major role in many of its effects. It moderately blocks NMDA and β2-subunit-containing nACh channels, weakly inhibits AMPA, kainate, GABAC, and 5-HT3 receptors, and slightly potentiates GABAA and glycine receptors. It has also been shown to activate two-pore-domain K+ channels. While N2O affects quite a few ion channels, its anaesthetic, hallucinogenic, and euphoriant effects are likely caused predominantly or fully via inhibition of NMDAR-mediated currents.

The Nitrous Oxide experience contains a complex and wide array of effects which based on the predefined potential subjective effects index found here, I will now begin to breakdown and describe.

Subjective effects:

Physical effects

The physical effects of Nitrous Oxide can be broken down into eight components all of which progressively intensify proportional to dosage.

  • Spontaneous tactile sensations - the nitrous oxide body high starts off as the sensation of a mixture of cold, warm, sharp and soft tingles which begin across the head and face at lower dosages but spread out across the body at higher dosages.
  • Suppression of touch - this partially to entirely suppresses ones own sense of touch creating feelings of numbness within the extremities. It is responsible for the anaesthetic properties of this substance.
  • Loss of motor control - a loss of gross and fine motor control along side of balance and coordination is prevalent within nitrous and becomes especially strong at higher dosages. This means that one should be sitting down before the onset unless they are experienced in case of falling over and injuring oneself.
  • Euphoria - this results in feelings of physical euphoria which range between mild pleasure to powerfully all encompassing bliss. Anecdotal reports show that this sensation which is taken advantage of by recreational users during sexual activity’s and said to greatly enhance orgasm.
  • Changes in felt bodily form - this usually occurs with higher dosages and can be described as feelings that in a non painful fashion your body’s physical form is being stretched into infinity, compressed into a singularity or split into two separate halves.
  • Weightlessness - this creates the sensation that body is floating and has become entirely weightless. It is often accompanied by feelings of slowly falling or drifting.
  • Dizziness - although uncommon some people report dizziness under the influence of nitrous.
  • Head aches - although uncommon a certain subset of people report headaches during the offset of Nitrous Oxide. If this occurs one should avoid this substance in the future.

Cognitive effects:

The cognitive effects of nitrous oxide can be broken down into 4 separate subcomponents which are listed and described below.

  • Laughter - this effect is extremely powerful and pronounced within nitrous oxide and can be described as sudden bouts of intense laughter and giggling. It is an effect which is especially prevalent when taken in the context of appropriate social settings.
  • Euphoria - this can be described as feelings of mild to intense happiness and general positivity.
  • Ego suppression, loss and death - at higher dosages, level 3 ego death is an all encompassing effect within nitrous oxide. In comparison to other hallucinogens, it is unique in style due to its rapid onset and fast comedown. This creates the experience that one’s sense of self is rapidly disintegrated and then suddenly restacked through a process of regaining one’s own long term memory. This is a remarkably identical process every time the experience is undergone.
  • Deja-vu - although uncommon a certain subset of people report strong feelings of deja-vu consistently when under the influence of Nitrous Oxide.
  • Amnesia - at high dosages, it is often common for one to experience amnesia and memory loss after the experience has occurred. This is especially prevalent alongside of ego death.
  • States of unity and interconnectedness - during high dosage states of ego death, this component is a common but inconsistent accompanying effect. It generally occurs at level 4 - 5 and creates experiences of becoming one with the greater whole. In comparison to other hallucinogens which induce this effect, it can be described as comparatively simpler and less profound due to its more basic accompanying cognitive effects.

Visual effects:

In comparison to other dissociatives such as Ketamine or DXM, the visual effects of nitrous oxide are comparatively simplistic. They progressively intensify proportional to dosage and can be broken down into five individual components which are listed and described below.

  • Decreased visual acuity - blurred vision to the point of all encompassing blindness is a completely consistent effect within nitrous oxide even at moderate dosages.
  • Double vision - this component is also prevalent at moderate dosages and makes reading incapable unless one closes an eye.
  • Suppression of pattern recognition - this effect generally occurs at higher dosages and makes one unable to recognize and interpret perceivable visual data.
  • Geometry - nitrous oxide geometry can be described as unique in its behaviour. It usually only occurs at higher dosages and as a static wall of geometry which appears in front of one’s vision alongside of the physical sensation of becoming and merging with it. It usually manifests as consistently incidental in its form but varies in its arrangement between people. In terms of its stylistic appearance it can be described as simplistic in complexity, organic in style, unstructured in arrangement, colourful in scheme, glossy in shading, soft and blurred in its edges, large in size, still in movement, rounded in corners, immersive in depth, and often based upon complex interlocking circles.
  • Hallucinatory states - in comparison to other more classical dissociatives, hallucinations are particularly rare with nitrous but possible at high dosages. They exclusively occur at high levels, are capable of manifesting as both external and internal in style, and are usually delirious in believability (but commonly only include mundane scenarios such as perceiving and talking to people who are not currently present).

Auditory effects:

The auditory effects found with nitrous oxide, although simplistic, are famously known to be particularly intense and consistent in their manifestation when compared to other hallucinogens. These effects include:

  • Distortions - these distortions are very powerful and loud enough in their volume to make the original sound completely unrecognisable. They include phasers, white noise, high pitch tones and notes, flanging, changes in pitch, echo effects, and stuttering.
  • Suppression - this effect can be described as a muffling and quieting of externally sourced sound which results in it sounding more indistinct and distant than it would usually be.

In combination with:

One of the most interesting application for nitrous oxide is not by itself but in combination with other hallucinogens to which it acts as a powerful and profound temporary potentiation of subjective effects.

  • Psychedelics - when taken in combination with a classical psychedelic such as LSD or psilocin, the effect will be a sudden and dramatic increase in perceived geometry to its maximum level of 7A or 7B. This is alongside of a sudden and dramatic ego death.
  • Dissociatives - when taken in combination with a classical dissociative such as MXE or DXM, the effect will be a sudden and dramatic increase in disconnective effects and the triggering of a sudden internal hallucinatory scenario.
  • Cannabis - when taken in combination with cannabis, the overall effects of the nitrous itself are potentiated more so than the effects of the cannabis.
  • Alcohol - when taken in combination with alcohol, negative side effects such as confusion, dizziness, and headaches are often greatly increased.

Available forms:

  • Canned whipped cream - these are found in any grocery store. They contain very minimal gas with one or two uses before the cream comes out.
  • Chargers - these are freely available and cheap to purchase online. They are small metal canisters which can be used by a nitrous cracker to fill a balloon full of gas which is then inhaled. Some varieties contain industrial residue and strength varies (as it is food grade).
  • Medical tanks - these are hard to find and dangerous without a professional. They are occasionally seen at music festivals being used to fill balloons for sale.

Toxicity and Harm Potential:

Nitrous oxide has been safely used as a mild anaesthetic for over 150 years. Problems with its use come primarily from carelessness. Potential problems include:

  • Brain injury and suffocation can result from lack of oxygen. When used as an anaesthetic, nitrous is always administered in combination with oxygen. Never use nitrous in any manner that does not provide for adequate oxygen intake.
  • Very cold temperatures of the gas can freeze the lips and throat if taken directly from a tank or whippit. Releasing the gas into a balloon first allows the gas to warm before being administered.
  • Heavy and frequent long term nitrous use can deplete vitamin B12 in the body and lead to serious and unpleasant neurological problems. Users may experience numbness and tingling in the fingers, toes, lips, etc. In more severe cases, there will be numbness of all extremeties. Taking B12 supplements, especially in combination with a multivitamin and complete amino acid supplements, may help alleviate this problem. If you experience these symptoms, cease nitrous use immediately and if the symptoms persist, seek medical attention.
  • Nitric oxide, a toxic industrial gas, is occasionally mistaken for nitrous oxide. Users should be careful they know what they are inhaling. Inhaling Nitric Oxide can permanently damage the lungs or kill.

Legal issues:

  • United states - possession of nitrous oxide is legal under federal law and is not subject to DEA purview. It is, however, regulated by the Food and Drug Administration under the Food Drug and Cosmetics Act. Prosecution is possible under its “misbranding” clauses, prohibiting the sale or distribution of nitrous oxide for the purpose of human consumption. Many states have laws regulating the possession, sale, and distribution of nitrous oxide. Such laws usually ban distribution to minors or limit the amount of nitrous oxide that may be sold without special license. For example, in the state of California possession for recreational use is prohibited and qualifies as a misdemeanour.
  • New Zealand - the Ministry of Health has warned that nitrous oxide is a prescription medicine, and its sale or possession without a prescription is an offence under the Medicines Act. This statement would seemingly prohibit all non-medicinal uses of the chemical, though it is implied that only recreational use will be legally targeted.
  • India - for general anaesthesia purposes, nitrous oxide is available as Nitrous Oxide IP. India’s gas cylinder rules (1985) permit the transfer of gas from one cylinder to another for breathing purposes. 

Conclusion:

In conclusion, although short lived nitrous oxide is an extremely fascinating and worthwhile substance. It is best used in combination with other substances to experience the full effects and is a worthwhile substance for anybody who is interested in the exploration of consciousness.

Click here for a more comprehensive breakdown.

DOM, broken down and described

Dosage (oral)

Threshold : 0.5 - 1mg
Light : 1 - 2mg
Common : 3 - 5mg
Strong : 8 - 10mg
Heavy : 10+mg

Duration (oral)

Total Duration : 12 - 16 hours
Onset : 20 - 90 minutes
Come up : 1 - 2 hours
Peak : 8 - 12 hours
Come down : 1 - 3 hours
After effects : 2 - 4 hours

2,5-Dimethoxy-4-methylamphetamine (DOM) or STP is a psychedelic drug of the substituted phenethylamine and substituted amphetamine chemical classes. It is a member of the DOx family of compounds. The phenethylamine equivalent (lacking the alpha-methyl group) is 2C-D.

This substance was first used recreationally in the mid-1960s and has little to no history of human usage prior to the 1991 publication of its synthesis and pharmacology in the PiHKAL (Phenethylamines i Have Known And Loved) by Alexander Shulgin. In modern times, it is used as a recreational drug and an entheogen, rarely sold on the streets and almost exclusively obtained as a grey area research chemical through the use of online vendors.

In terms of its pharmocology, DOM acts as a selective 5-HT2A, 5-HT2B, and 5-HT2C receptor partial agonist. Its psychedelic effects are mediated via its actions on the 5-HT2A receptor. Due to its selectivity, DOM is often used in scientific research when studying the 5-HT2 receptor subfamily.

DOM is a highly dose sensitive psychedelic that is often sold on blotting paper and known for its strong visuals and intense body load. Many reports also indicate that the effects of this chemical may be overly intense for those who are not already experienced with psychedelics.

The DOC experience contains a complex and wide array of effects which based on the predefined potential subjective effects index found here, I will now begin to breakdown and describe.

Physical effects:

The physical effects of DOM can be broken down into six components all of which progressively intensify proportional to dosage. These are described below and generally include:

  • Spontaneous tactile sensations - The body high of DOM is manifested as somewhat intense in comparison to most classical psychedelics, however in comparison to DOC and the overwhelming forcefulness of 2C-E, it can actually be considered quite mild. The sensation itself can be described as a constantly present yet somewhat mild energetic pins and needles sensation that encompasses a person’s entire body. This is coupled with a euphoric, fast moving, sharp and location specific tingling sensation. It is usually felt over every square inch of the skin but occasionally manifests itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves.
  • Stimulation - In terms of its effects on the physical energy levels of the tripper, DOM is usually considered to be extremely stimulating at levels which do not become overwhelming, resulting in a shakiness and unsteadiness of the hands but encouraging trippers to move around, run, dance, climb and generally engage in physical activities. In comparison, other more commonly used psychedelics such as psilocin are generally sedating and relaxed.
  • Increased bodily control
  • Enhancement of touch - Feelings of enhanced tactile sensation are consistently present at moderate levels throughout most DOM trips. Once Level 7A visuals are reached, an intense sensation of suddenly becoming aware of and being able to feel every single nerve ending across a person’s entire body all at once is consistently present.
  • Nausea - Mild to extreme nausea are reported when consumed in moderate to high dosages and either passes once the tripper has vomited or gradually fades by itself as the peak sets in.
  • Vasoconstriction - This effect is usually only present at higher dosages but can be particularly uncomfortable.

Cognitive effects:

The head space of DOM is described by many as one of extreme mental stimulation and a powerful enhancement of a person’s current mental state.

The total sum of these cognitive components regardless of the setting generally includes:

  • Introspection - This component is consistently manifested only in the context of a non-social setting in which the user is alone.
  • Increased empathy, love and sociability - This component is consistently manifested only in the context of social settings in which one is within the company of others. These feelings of sociability, love and empathy are a little weaker and less sharp than those found on substances such as MDMA and 2C-B but still prove strong enough to provide long lasting therapeutic effects.
  • Acceleration of thought
  • Time distortion
  • Feelings of fascination, importance and awe
  • Conceptual thinking
  • Connectivity of thought
  • Enhancement of current mind state
  • Removal of cultural filter
  • Ego suppression, loss and death

Visual effects:

Enhancements

DOM presents a full and complete array of possible visual enhancements which generally includes:

  • Increased visual acuity
  • Enhancement of colours
  • Enhanced pattern recognition

Distortions

As for visual distortions and alterations, the effects experienced are detailed below:

  • Visual drifting (melting, flowing, breathing and morphing) - In comparison to other psychedelics, this effect can be described as highly detailed, slow and smooth in motion, static in their appearance and unrealistic/cartoon like in style.
  • Tracers
  • After images
  • Texture repetition
  • Colour shifting
  • Scenery slicing

Geometry

The visual geometry that is present throughout this trip can be described as more similar in appearance to that of 4-AcO-DMT or ayahuasca than that of LSD, 2C-B or 2C-I. They can be comprehensively described as structured in their organization, organic in geometric style, intricate in complexity, large in size, fast and smooth in motion, colourful in scheme, glossy in color, sharp in their edges and equally rounded and angular in their corners. They give off a contradictory natural and synthetic feel to them that at higher dosages are significantly more likely to result in states of Level 7B visual geometry over Level 7A.

Hallucinatory states

DOM and other substituted amphetamines produce a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics. This holds particularly true in comparison to other substances within the phenethylamine family. These effects include:

  • External hallucinations
  • Internal hallucinations - In comparison to other psychedelics such as LSD, DOM is extremely high in imagery embedded within visual geometry. This particular effect commonly contains hallucinations with scenarios, settings, concepts and autonomous entity contact. They are more common within dark environments and can be described as internal in their manifestation, lucid in believability, interactive in style and almost exclusively of religious, spiritual, mystical or a transcendental nature in their overall theme.

Auditory effects:

The auditory effects of DOM are common in their occurrence and exhibit a full range of effects which commonly includes:

  • Enhancements
  • Distortions
  • Hallucinations

Health effects, addiction potential and tolerance:

The toxicity and long term health effects of recreational DOM have been studied in a very limited amount of scientific context and the exact toxic dosage is unknown. This is because DOM is a research chemical with very little history of human usage. Anecdotal evidence from people who have tried DOM within the psychedelic community suggests that there are no negative health effects attributed to simply trying this drug at low to moderate doses or using it very sparingly (but nothing can be completely guaranteed).

DOM is not physically addictive and many users experience a frequency self-regulating quality to the drug. Tolerance for DOM seems to be very mild and does not build up without repeated use over a short period of time.

Legal issues:

  • UK: DOM is a Class A drug.
  • USA: DOM is a Schedule I drug.
  • Canada: DOM is a Schedule I drug.
  • New Zealand: DOM is a Class C drug.
  • Belgium: DOM is a Schedule I drug.

Conclusion:

In conclusion, DOM is a very worthwhile compound and I was intrigued by its ease in ability to invoke higher level visual and cognitive effects. It deserves its place in Shulgin’s magical half dozen and (while long-lasting) is definitely one of the more interesting and unique phenethylamines I have tried.

This substances subjective effect breakdown was contributed by PsychonautWiki admin, Cocoanatta.